Are You Still Using Lenses for Cell Counting? JLM-Lifetech BC1600: The Era of Lens-Free Chip Microscopy Has Arrived!

In the evolution of cell science and bioprocessing, our understanding of cell populations is advancing from mere "quantity statistics" to deep "quality insights." However, traditional cell observation methods have long been bottlenecked by the inherent conflict between "field of view (FOV)" and "resolution."

How can we obtain both the panoramic distribution of a cell population and the fine morphology of a single cell in a single test? JLM-Lifetech’s answer is: let the cells project and image themselves!

Based on VPS lens-free imaging technology, the JLM-Lifetech BC1600 series cell counter and analyzer integrates a VPS vertical charge transfer imaging chip, completely abandoning optical lenses. Utilizing a high-performance VPS chip with up to 600 million pixels, it completely reinvents the underlying logic of cell imaging. A single scan covers an ultra-large field of view of up to 100mm² with a resolution of 500 nm-equivalent to the clarity of a traditional microscope's 30X objective lens. Through "lens-free" ultra-wide FOV imaging and AI-powered smart analysis, it brings a revolutionary and disruptive experience to your cell research.

• VPS Lens-Free Imaging: No lens, no focusing, and no disposable counting slides required.
• Ultra-Large Detection Area: Covers up to 100mm².
• High Resolution: Equivalent to a 300X optical lens resolution.
• Multi-Attribute Detection: Live/dead analysis, morphology, particle size, circularity, and more.
• Debris & Impurity Differentiation: Effective filtering for microbiological risk monitoring.
• Advanced Automation: Fully automated, high-throughput, AI software, and 21 CFR Part 11 compliance.

• Nanometer-Scale Pixels, Subcellular Resolution: Powered by Vertical Charge Transfer (VPS) technology, the chip's pixel size is as small as 0.5μm. It achieves high-definition resolution of subcellular structures without any optical lenses.
• Ultra-Large Field of View (FOV)—No More "Looking Through a Straw": A single imaging scan captures a field of view of up to 100 mm², matching the clarity of a traditional 30X objective. You no longer need to stitch images together; a single capture yields a complete, panoramic cell distribution map.
• Semiconductor-Grade Stability: Built on mature semiconductor manufacturing processes, the VPS chip delivers imaging consistency and reproducibility far exceeding traditional optical systems, ensuring every detection is precise and reliable.

Traditional microscopes rely on complex optical paths with objectives and eyepieces, which are not only high-cost and difficult to maintain, but also limited by the physical law that "field of view and resolution cannot be optimized simultaneously."

The BC1600 series cell counter and analyzer utilizes "lens-free" chip microscopy. After light passes through the sample, it projects directly onto the surface of the VPS chip, where the 0.5μm nanometer-scale pixel units capture the image directly.

• What You See Is What You Get: No focusing or objective lens swapping required. The sample images automatically once loaded onto the device, achieving true "load-and-test" convenience.
• Ultra-Large FOV + HD Details: A single scan covers up to 100mm² while simultaneously delivering crisp details of cell outlines, nucleocytoplasmic ratios, and particle distribution. This achieves "panoramic observation" and "microscopic insight" at the same time.

Leveraging the massive amounts of high-definition image data provided by the VPS chip, the BC1600 series cell counter and analyzer transitions from simply "counting numbers" to "analyzing status."

• Hundreds of Millions of Pixels for Panoramic Scanning, Delivering Highly Reliable Statistics: Supported by an imaging scale of hundreds of millions of pixels, the system quickly completes a panoramic scan of the sample. The large sample size statistics effectively eliminate the deviations caused by random sampling in small fields of view.
• High-Contrast Imaging for Precise Viability Analysis: Traditional brightfield imaging often lacks sufficient contrast when distinguishing between live and dead cells. However, the VPS chip imaging system of the BC1600 series generates extremely high-contrast cell images. This means that even when using Trypan Blue dye alone, the system can clearly and stably distinguish between stained and unstained cell populations, enabling precise and reliable assessment of cell viability.

In the field of life sciences, AI-driven cell morphology analysis has become a key tool for enhancing quality control. The BC1600 series cell counter and analyzer supports:

• AI-Driven Multi-Parameter Analysis: Automatically performs multi-parameter analysis, statistical calculations, and report generation for cell morphology.
• Customized Deep Learning: Supports customized deep learning model training. For cells with special morphologies or rare particles, users can import data to train their own exclusive recognition models for highly accurate, one-step detection.
• Building a Data Ecosystem: Supports multiple operating terminals (local PC, tablet, and cloud servers) to enable local storage, cloud synchronization, and cross-platform analysis of data. Whether for daily laboratory testing or multi-center collaborative research, data flows securely and efficiently.

The BC1600 series cell counter and analyzer is available in two models: the standard version (BC1600 Auto) and the portable version (BC1600 Lite), catering to everything from high-throughput laboratories to on-site rapid testing.

Now, let us explore more possibilities of cells together with this innovative "chip" technology!